The anti-ageing system for every age
With Z Fill there is an effective and long-lasting option for restoring a youthful and fresh appearance, adding volume and treating wrinkles.

Only the highest quality deserves your trust
The purest hyaluronic acid of non-animal origin is the basis of the new Z Fill generation. The series of products includes five injectable fillers, two with lidocaine.

Tested quality, made in Europe
The five hyaluronic acid fillers of the Z Fill series are manufactured according to strict European quality and safety standards. They comply with the ISO 13485 directive. The toxicological investigations and tests of biological compatibility are performed in accordance with the ISO 10993 series of standards.

Long-lasting effect through a high degree of stability
The gels acquire maximum stability through an innovative, multi-stage manufacturing process. This slows down the body’s own degradation processes and guarantees a long-lasting effect. A rejuvenating effect can be seen immediately after the hyaluronic acid therapy. Z Fill activates lasting revitalisation of ageing skin. It compensates for the age-related hyaluronic acid deficit and systematically hydrates the dermis.


Virtually painless – through the addition of lidocaine

Treatment regions:

  • Fill hyaluronic acid fillers were developed to:
  • Gently correct wrinkles and creases
  • Compensate for a loss of volume
  • Improve lip volume and shape
  • Shape and sculpt natural facial contours
  • Improve complexion and the elasticity of the skin
  • Improve the skin’s moisture levels and its overall appearance
  • Perform cosmetic treatments, such as scars

Optimal skin compatibility
The use of hyaluronic acid of non-animal origin and the strict safety requirements guarantee a pure and safe product.

Satisfied patients
Nearly 98% of patients are satisfied with our products and would recommend a treatment to their friends.¹

Immediately visible
With Z Fill you see immediate, natural results, without the risk of a change to or loss of your natural facial expressions.

Painless treatment
Most people find filler injections to be relatively painless. The addition of lidocaine, a mild anaesthetic, to certain products makes the injection even more pain-free for you.


¹ Kopera D, 2015. An open-label uncontrolled, multicenter study for the evaluation of the efficacy and safety of the dermal filler Princess® VOLUME in the treatment of nasolabial folds. Biomed Res Int, 2015, 195328.

Please note the different indications of the individual hyaluronic acid fillers.

Ultimate purity for maximum safety

  1. The basis for ZFill is pure, bio-fermentatively obtained hyaluronic acid of non-animal origin. A special method first carefully aligns the molecular chains to each other. 
  2. Crosslinking: Through the addition of BDDE, crosslinks form between the hyaluronic acid chains.
    A very dense, three-dimensional matrix develops and the gel gains stability and resistance to the degradation processes of the skin – this explains the long-lasting effect of ZFill contour2, ZFill contour+, ZFill deep2 and ZFill deep+.
  3. The preparation is then homogenised. The gel is now viscous and yet extremely flexible and elastic – ideal for an even and controlled injection with thin cannulas.
  4. A complex purification process follows. All excess and harmful components (unbound BDDE, proteins, and endotoxins) are carefully removed.
    Result:Exceptional purity which goes far beyond the strict requirements of the European directive for medical devices. 
  5. In the final step, the filled gel syringes are sterilised in a steam autoclave. 
  6. To ensure that the syringes are free of particles, each individual syringe undergoes another visual inspection. Only after the necessary production and safety tests according to the latest European standards is the respective ZFill batch released.

Your questions – Our answers

When is the effect visible?
The results can be seen directly after the treatment.

How long does the treatment take?
The duration depends on the area to be treated and takes between 15 and 30 minutes.

What happens during the treatment?
Your doctor uses a very fine needle to inject the Z Fill preparation directly into the skin. Depending on the area to be treated, the injection is performed very superficially or in the deeper layers of skin.

Is the treatment painful?
Thanks to the gel-like substance of the Z Fill preparations, the injection is extremely gentle and therefore virtually painless. Depending on individual pain sensations, treatment with cold air can be performed beforehand and as a follow-up treatment. This has been demonstrated to reduce pain. Ask your doctor about this treatment option. An anaesthetic ointment as well as a cooling gel can also be used.
Through the addition of lidocaine, a mild anaesthetic, in the crosslinked products, pain is significantly reduced during injection into the skin.

What must I keep in mind following the treatment?
You can resume your regular daily routine directly following the treatment. Within the first week after treatment, sunbathing, tanning booths and saunas as well as laser and IPL treatments should be avoided.


The virtually painless Z Fill concept

To achieve optimal treatment results, the products, like all conventional injectable implants, should be injected carefully but quickly.

Studies have shown that cooling with the Cryo 6 cold air device reduces patients’ sensitivity to pain. As a result, the treatment is much better tolerated. Following the procedure, the treated area is massaged using gentle pressure to ensure even distribution of the product.

The facial muscles should be utilised as little as possible for up to 2 hours after the treatment in order to facilitate the integration of the implant in the surrounding cell network. Brief subsequent cooling of the treated area can additionally reduce the development of swelling and redness.


Intended use and indications not valid for the USA.


Information about possible risks and adverse effects as well as warnings can be found in the instructions for use.